Vol. 7, Issue 01
January 10, 2007 Cover
Cardiac fibroblast cells (stained green and imaged by fluorescence microscopy, left
column) reorganize their local collagen environment to generate strain fields (colored maps, right
column; tensile strain is red, compressive is violet, zero strain is green) between themselves (overlays
of cells with strain fields; middle column). The strain fields are calculated from the changes in gold
nanorod position as a function of time, as measured by darkfield optical microscopy. The three rows
of data correspond to three different time points, spaced 20 min apart between rows. Microscopy data
were taken by John Stone and Patrick Sisco (both in the Department of Chemistry and Biochemistry,
University of South Carolina) and Edie Goldsmith (School of Medicine, University of South Carolina);
strain field maps were calculated by Sarah Baxter (Department of Mechanical Engineering, University
of South Carolina); composite images were generated by Christopher Robinson (Department of Art,
University of South Carolina). John W. Stone, Patrick N. Sisco, Edie C. Goldsmith, Sarah C. Baxter,
and Catherine J. Murphy, p 116.
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